← The catalogPG-1008 · Vol. II

— Monograph note —

Part of Clavicular's Looksmaxxing Stack

TB-500 is the systemic recovery peptide in Clavicular's looksmaxxing stack. The Wolverine duo with BPC-157.

The full stack →
TB-500 (Thymosin Beta-4) 10mg

Plate № PG-1008 — Reykjavík

Figure i · TB-500 (Thymosin Beta-4) 10mg — lyophilized plate

№ 01 — Monograph

Buy TB-500 (Thymosin Beta-4) 10mg

Synthetic Thymosin Beta-4 fragment — researched for actin regulation, satellite cell activation, and systemic tissue repair. The most studied systemic repair peptide available alongside BPC-157.

Priced from

$53.99

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Purity

≥ 98%

HPLC verified

Form

Lyophilized

Sealed vial

Ship

2–5 days

US, tracked

№ 02 — Specifications

CAS · 77591-33-4
Active Sequence
Ac-LKKTETQ (core actin-binding motif)
Full Name
Thymosin Beta-4 fragment (synthetic analogue)
Molecular Weight
2174.5 Da
Form
Lyophilized powder
Purity
≥98% (HPLC verified)
Storage
−20°C long-term / 4°C up to 4 weeks reconstituted
Reconstitution
Bacteriostatic water

№ 03 — Mechanism

How themolecule works

Actin Sequestration & Satellite Cell Activation

TB-500 is a synthetic analogue of the active Ac-LKKTETQ region of Thymosin Beta-4 (Tβ4), a 43-amino-acid peptide present in virtually all nucleated cells. Its primary mechanism is G-actin sequestration via the Ac-LKKTETQ motif — this promotes cell migration, angiogenesis, and tissue repair by controlling actin polymerization dynamics. TB-500 activates satellite cells (muscle stem cells), upregulates metalloproteinases for ECM remodeling, and reduces pro-inflammatory cytokines including TNF-α and IL-1β. Its systemic cell migration properties make it complementary to BPC-157's local angiogenic mechanism — the two are the most studied peptide repair combination in published literature. Multiple animal model studies demonstrate accelerated healing across skeletal muscle, tendon, cardiac tissue, and peripheral nerves. Molecular weight: 2174.5 Da.

№ 04 — Highlights

Why acquireTB-500 (Thymosin Beta-4) 10mg

01

Satellite Cell Activation

TB-500 promotes satellite cell (muscle stem cell) entry into the cell cycle and differentiation into myoblasts. In vitro and animal models demonstrate increased satellite cell proliferation at injury sites, driving muscle regeneration after damage. This makes TB-500 particularly relevant to skeletal muscle repair, atrophy recovery, and exercise-induced damage research.

02

Cardiac & Vascular Research

Multiple studies have examined Thymosin Beta-4 in cardiac repair post-infarction. Animal models demonstrate reduced cardiomyocyte apoptosis, improved neovascularization, and enhanced functional recovery after ischemic injury. TB-500's VEGF upregulation and endothelial cell migration promotion are the primary vascular mechanisms.

03

Synergy with BPC-157

TB-500 and BPC-157 are the most studied peptide combination in healing research. BPC-157 drives local angiogenesis and growth factor upregulation at injury sites; TB-500 drives systemic cell migration and actin regulation. The complementary pathways make the combination the standard benchmark in regenerative peptide research.

№ 05 — Correspondence

Questions,answered.

The letters we receive most frequently about this compound, with plain answers.

Q.01What is the difference between TB-500 and BPC-157?+

TB-500 (Thymosin Beta-4 fragment) primarily acts via actin sequestration and satellite cell activation — most relevant to muscle and connective tissue repair. BPC-157 acts via VEGFR2, FAK-paxillin, and nitric oxide pathways with a broader tissue profile including GI cytoprotection. They are frequently studied in combination for synergistic healing effects.

Q.02How does TB-500 differ from native Thymosin Beta-4?+

TB-500 is a synthetic fragment corresponding to the Ac-LKKTETQ core actin-binding region of the 43-amino-acid Thymosin Beta-4 peptide. It retains the primary biological activity of the parent peptide at a lower molecular weight, with comparable results in published research.

Q.03How should TB-500 be reconstituted?+

Add 1–2mL bacteriostatic water to a 10mg vial. At 1mL: 10mg/mL. At 2mL: 5mg/mL. Store reconstituted at 4°C, use within 4 weeks. Gently swirl — do not shake.

Laboratory Use Only. This compound is sold for in-vitro laboratory research and is not intended for human consumption, injection, or therapeutic use. Nothing on this page constitutes medical advice. Researchers are responsible for compliance with applicable regulations in their jurisdiction.

TB-500 (Thymosin Beta-4) 10mg

$53.99

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